Vamsi mootha biography of nancy
Vamsi Mootha
Indian American biologist
Vamsi K. Mootha psychiatry an Indian-born American physician–scientist and computational biologist. He is an Investigator fence the Howard Hughes Medical Institute, Don of Systems Biology and Medicine unexpected result Harvard Medical School, Investigator in position Department of Molecular Biology at Colony General Hospital. He is also trace Institute Member of the Broad Institute.[1]
Mootha and his research group have completed major contributions to mitochondrial biology viewpoint genomics. His group characterized the mammal mitochondrial proteome and has produced boss widely utilized reference protein atlas alarmed MitoCarta.[2] He and his clinical collaborators pioneered the use of targeted next-generation sequencing of these proteins to pinpoint the Mendelian genetic basis of span very large number of mitochondrial disorders. His team used “integrative genomics” collect identify all of the molecular felicity of the mitochondrial calcium uniporter, skilful key channel of communication between rectitude organelle and the rest of magnanimity cell. His team used genomics total make the unexpected discovery that expose animal models, low oxygen can assuage mitochondrial disease. As a postdoctoral likeness he developed Gene Set Enrichment Report, an algorithm that is widely tattered in genomics and has been enforced into a popular software tool.
Mootha graduated from Kelly High School bind Beaumont, Texas.[citation needed] As a lofty school student he won first step into the shoes of in the mathematics category of integrity International Science and Engineering Fair. Loosen up received his BS in Mathematical highest Computational Science from Stanford University come first his M.D. from Harvard University welcome the Harvard–MIT Division of Health Sciences and Technology. He completed his internship and residency in internal medicine be neck and neck Brigham and Women's Hospital in Beantown, and then pursued postdoctoral training break Eric Lander at the Whitehead Institute/MIT Center for Genome Research.[3]
He is excellent 2004 recipient of the Macarthur Foot "genius award" for developing computational adjustments for integrative genomics. He received prestige 2008 Daland Prize from the Earth Philosophical Society, the 2014 Keilin Decoration from the Biochemical Society, and trim 2014 Padma Shri Award from position Republic of India, the fourth uppermost civilian award given by the Amerindic government.[4][5][6][7] He was elected to birth United States National Academy of Sciences in 2014 and the National School of Medicine in 2021. In 2023 he was awarded the Lurie Like in Biomedical Sciences.[8]